Cholestasis of pregnancy, also called intrahepatic cholestasis of pregnancy (ICP), is a liver condition that happens when bile starts to build up in the liver. It can develop in late pregnancy and ...

Cholestasis of pregnancy is actually a fairly common condition. It affects 1 or 2 per 1,000 pregnancies in the United States. But unless you’ve had it before, you might not know very much about ...

Some 28% of participants with a history of neonatal cholestasis had definite/possible portal hypertension during the study, compared with 21% without a history of neonatal cholestasis (P =.16 ...

Odevixibat treatment reduced levels of peripheral blood autotaxin, pruritus and serum bile acid among pediatric patients with progressive familial intrahepatic cholestasis, according to pooled ...

The Food and Drug Administration (FDA) has approved Livmarli ® (maralixibat) for the treatment of cholestatic pruritus in patients 5 years of age and older with progressive familial intrahepatic ...

Cholestasis is the most common pregnancy-related liver disorder. Left untreated, it can cause fetal distress, hemorrhage and even stillbirth. By Christina Caron This story was originally published ...

Pregnant patients should discontinue use of thiopurines if they develop intrahepatic cholestasis of pregnancy. The use of thiopurines (eg, azathioprine, 6-mercaptopurine, and 6-thioguanine) by ...

First, how the accumulation of bile acids in the central nervous system (CNS) during cholestasis leads to damage to the blood-brain barrier, neuroinflammation, and neurodegeneration is discussed ...

BRIC is a rare disorder characterized by episodic cholestasis without evidence of significant liver injury. Typical symptoms include intense pruritus, jaundice, fatigue, weight loss, and ...