Development of a new nano-immune agonist to improve immunotherapy for melanoma, a challenging skin cancer, by changing the ...

Researchers have developed an innovative nano-immune agonist that significantly improves immunotherapy outcomes for ...

Our cells harbor a DNA detector termed cGAS to inform the immune system of viral and bacterial infections, cell death, as ...

The activation of cGAS-STING promotes the release and presentation of cancer antigens, T cell migration and infiltration, and T cell recognition and cytotoxicity. The cGAS-STING pathway also ...

Zhijian “James” Chen, a biochemist at the University of Texas Southwestern Medical Center, was awarded the 2024 Albert Lasker Basic Medical Research Award for the discovery of the cGAS ... of STING.

An artist's impression of cGAS-STING pathway response model for micronucleus. Before, cGAS's accumulation in micronuclei was considered to be an indicator of cGAS activation. Now, it was found ...