Functional CFH is critical to prevent excessive activation of the complement system in the circulation. Using numerous unique mouse models, the researchers dissected the role of CFH in ...

The complement system, of which CFH is a modulator, is dysregulated in patients with these risk variants, and results in amplification of aberrant inflammatory responses in the eye.

The complement system, of which CFH is a modulator, is dysregulated in patients with these risk variants, and results in amplification of aberrant inflammatory responses in the eye.

Complement is an amplifier of the innate immune system composed of around 30 components, and CFH functions to control complement’s activity. The hypothesis is that complement hyperactivity ...

Three separate teams of scientists all pinpointed a gene called CFH for complement factor H. It is involved in a component of the immune system that regulates inflammation.

This system is poorly studied and the association between IDO and CFH has never been discovered for any cancer prior to our study." Derek Wainwright, PhD, Senior Author ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, No. 46 (Nov. 14, 2006), pp. 17456-17461 (6 pages) Polymorphisms in the complement factor H gene (CFH) are ...

No sign of complement activation was noted in plasma (C3 level, 1.15 g per liter), the plasma CFH antigenic level was normal, and no abnormalities were found in the genes CFH or CFHR1 through CFHR5.