A genomic study of human and selected nonhuman primate centromeres has revealed their unimaginable diversity and speed of evolutionary change. In cell genetics, a centromere is the spot where two ...

Scientists have solved a decade-long question about the mechanism that preserves the centromere, the hub that ensures DNA ...

With a few exceptions, eukaryotic chromosomes have a single centromere that ensures their accurate segregation during mitosis. Chromosomes that lack centromeres segregate randomly during mitosis ...

In the absence of DDM1 and RNAi, this TE doesn’t produce small RNAs, so the centromere is not methylated. These mutants also had few epigenetic tags on their histones, which contribute to the ...

The pairs of chromosomes that have been replicated are called sister chromatids, and they remain joined at a central point called the centromere. A large structure called the mitotic spindle also ...

They found that two protein complexes work together to determine the centromere distribution during cell division: condesin II (CII) and the linker of nucleoskeleton and cotoskeleton (LINC). “The ...