Next-generation sequencing (NGS) has transformed immune profiling, enabling deeper characterization of disease mechanisms, ...

Reference: Kabir MF, Karami AL, Cruz-Acuña R, et al. Single cell transcriptomic analysis reveals cellular diversity of murine esophageal epithelium. Nat Commun. 2022;13 (1):2167. doi: ...

UZH researchers have now investigated the emergence of cellular diversity in real time. Cells are the smallest units of life. But even within the same tissue or organ, they are not all identical.

“During tissue formation, dynamic cell shape changes drive morphogenesis while asymmetric divisions create cellular diversity,” Herbert and Lovegrove said in a study recently published in Science.

Background The rapid advancement of single-cell and single-nucleus RNA sequencing (sc/snRNA-seq) has opened unprecedented windows into cellular diversity, yet existing methods for multiplexing ...

“During tissue formation, dynamic cell shape changes drive morphogenesis while asymmetric divisions create cellular diversity,” Herbert and Lovegrove said in a study recently published in Science.