During embryonic stem cell (ESC) development, pluripotent stem cells transition from a naïve state into a primed state before they take their first steps toward a lineage commitment. Jacob Hanna, a ...

A stem-cell derived human embryo model showing blue cells (embryo), yellow cells (yolk sac) and pink cells (placenta). Scientists have grown an entity that closely resembles an early human embryo ...

Scientists have created a stem cell-derived model of the human embryo in the lab by reprogramming human stem cells. The breakthrough could help research into genetic disorders and in understanding ...

A 6-day-old embryo model from Jacob Hanna’s lab in Israel has structures akin to ones found in human embryos 12 days after fertilization. Those structures include a ball of cells (top, purple ...

Human embryos are extremely difficult to study. This lack of samples limits our understanding of crucial developmental stages, such as the early formation of blood cells. A stem-cell-based model ...

The embryo model was then left to grow until it could be compared to an embryo 14 days after fertilization. In most countries, this is the cut-off for normal embryo research under law.

Recent breakthroughs in making stem-cell based human embryo models are raising urgent questions about to what extent they should be treated like natural embryos and whether they are open to misuse.

While previous models mimicked pre-embryos, Hyun said the latest ones model an embryo after it has implanted in the uterus. Real human embryos can be extremely hard to see at that stage because ...

Letting the embryo model say “Go!” Hanna’s team built on their previous experience in creating synthetic stem cell–based models of mouse embryos. As in that research, the scientists made no use of ...

For several years, researchers studied human embryonic stem cells (ESCs) to understand the unique features of these pluripotent cells, but on their own, they poorly resembled the complex structures ...

Embryo models differ from an actual embryo in that they are stem cell-based, so they can be made easily and in high numbers, according to the Francis Crick Institute in London.

The stem cell-based embryo model and actual human embryos share many characteristics but are distinctly different. However, internationally, not everyone agrees on the definitions and what we ...