An international team led by researchers at the University of Toronto and the Broad Institute of MIT and Harvard has assembled the first large-scale, publicly available map to show the impact of ...

The majority of mutated cells contained only one or two copy number alterations, and it’s known that it takes multiple mutations to form a cancer. However, in some women carrying high-risk genetic ...

A new proof-of-concept method reliably engineered a hotspot mutation of SF3B1, a gene-splicing gene, into diverse cancer cell lines, outperforming other contemporary editing approaches.