Mapping the Human Cell In a recent paper in the journal Nature, Ideker and his colleagues presented their latest attempt to fill this information gap: a fine-grained map of a human cell, showing ...

A new proof-of-concept method reliably engineered a hotspot mutation of SF3B1, a gene-splicing gene, into diverse cancer cell lines, outperforming other contemporary editing approaches.

Adding a second checkpoint inhibitor to chemotherapy improves outcomes among patients with non–small cell lung cancer (NSCLC) who have STK11 and/or KEAP1 mutations, according to the authors of a ...

Two patients with BRAF class 3–mutated metastatic non–small-cell lung cancer (NSCLC) were treated with erlotinib at our Institution after failure of standard therapies. Two cell lines were established ...