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New findings are calling into question a long-held theory for how a dividing cell decides to stop the process of mitosis and restart the cell cycle. Chromosomes (blue) and mitoticspindle (green) ...
The cell cycle is understood to be the stages through which a cell progresses to ultimately divide into separate cells. It is this process that underlies the proliferation of life - and is ongoing ...
By separating these cells based on their FUCCI signals, the researchers identified differences in gene expression patterns at different cell cycle stages in vitro. Furthermore, they demonstrated ...
3'RNA sequencing was performed in 1,733 patients from the PETACC-8 trial and 1,248 patients from the IDEA-France trial. Four transcriptomic signatures were analyzed: T-cell and macrophage M2 ...