The lower image shows the structure of the thin filament spanning across several sarcomere regions. Scale bar shows 50 nm.

Structure of the native myosin filament in the relaxed cardiac sarcomere Journal: Nature Published: 2023-11-01 DOI: 10.1038/s41586-023-06690-5 Affiliations: 4 Authors: 11 Go to article ...

Atrial fibrillation, heart failure and stroke -- hypertrophic cardiomyopathy can lead to many serious health conditions and is a major cause of sudden cardiac death in people younger than 35.

In their current study the scientists produced the first high-resolution image of the cardiac thick filament spanning across several regions in the sarcomere. “With 500 nanometer length this makes for ...

In their current study the scientists produced the first high-resolution image of the cardiac thick filament spanning across several regions in the sarcomere. “With 500 nm length this makes for ...

In a heartbeat, cardiac muscle cells contract to push blood out to the body, then relax to allow the heart to fill again. This is possible because muscle proteins are organized into sarcomeres, which ...

The addition of TBX20 promoted cardiac reprogramming, as seen in activation of cardiac genes related to sarcomere structure, ion channels and heart contractions.

However, supplementation with β-hydroxybutyrate or overexpression of Hmgcs2 improved these defects, which restored sarcomere structure, mitochondrial function, and adenosine triphosphate (ATP ...

Cardiac structure and function significantly correlated with risk of kidney failure with replacement therapy, according to data published in the American Journal of Kidney Diseases.“Heart ...

Valsartan, an angiotensin II receptor blocker drug, delayed disease progression and improved cardiac structure and function in patients with early-stage hypertrophic cardiomyopathy, according to ...