New research from the University of Missouri School of Medicine reveals more information about this vital function and how it ...

Key Points GAAP revenue surged to $66.8 million in Q2 2025, driven by recognition of one-time license and milestone payments, exceeding analyst estimates by 3,065.9% (GAAP). GAAP loss per share ...

Each cardiac muscle cell can have over 5,000 sarcomeres, which compounds both the shortening and relaxation events. “This process appears to be regulated by myosin binding protein-C (cMyBP-C), which ...

This specificity was further underscored by F10's differential impact on ATPase activity across various myosin isoforms in different muscle types, highlighting its specificity for cardiac myosin ...

The structure of thick filaments of vertebrate cardiac and skeletal muscle was outlined 60 years ago 3. Myosin comprises two pear-shaped ‘heads’ attached to a tail that measures approximately ...

Edgewise Therapeutics, Inc., (Nasdaq: EWTX), a leading muscle disease biopharmaceutical company, today reported financial results for the second quarter of 2025 and recent business highlights.

“Our pioneering science relating to the mechanics of cardiac muscle function continues to be the engine empowering Cytokinetics as we advance our specialty cardiology franchise focused on myosin ...

Hypertrophic cardiomyopathy β-cardiac myosin mutation (P710R) leads to hypercontractility by disrupting super relaxed state. Proceedings of the National Academy of Sciences, 2021; 118 (24 ...

New Findings from Studies of Cardiac Myosin Inhibitors in Animal Models of Hypertrophic Cardiomyopathy and Heart Failure with Preserved Ejection FractionSOUTH SAN FRANCISCO, Calif., Nov. 16, 2020 ...

The protein's primary job is to provide the muscle-motor action that pumps blood. The real breakthrough of this study is that we've discovered another major biologic activity of cardiac myosin.