The sarcomere is the most basic contractile unit in skeletal and cardiac muscle. Mutations in genes encoding sarcomeric proteins give rise to heritable myopathies, although muscle function is more ...

A single myosin filament connects to two actin filaments on either side, forming a single unit of muscle tissue known as a sarcomere. Intercalated discs connect cardiac muscle cells. Gap junctions ...

"The heart muscle is a central engine ... the first high-resolution image of the cardiac thick filament spanning across several regions in the sarcomere. "With 500 nm length this makes for the ...

BACKGROUND: Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately associated with other organelles, particularly the reciprocal regulation ...

"The heart muscle is a central engine ... the first high-resolution image of the cardiac thick filament spanning across several regions in the sarcomere. "With 500 nm length this makes for the ...

A new technique now makes it possible to look much more closely at how sarcomeres, the basic building blocks within all skeletal and cardiac muscles ... isolate a single sarcomere, watch it ...