A new type of tissue-engineered cardiac patch could not only seal defective areas of the heart, as has been the case up to ...

Researchers have examined the early stages of heart development, showing how complex meshes of muscle grow to form a complex ...

One promising strategy to remuscularize the injured heart is the direct cardiac reprogramming of heart fibroblast cells into cardiomyocytes. Researchers have identified TBX20 as the key missing ...

In their experiment, Xu's team assembled bundles of heart muscle cells into microscopic three-dimensional spheroids that mimicked the structure and function of the human heart. The team froze the ...

Direct reprogramming is a potential therapy for heart attack patients. In vitro, TBX20 improved contractility and mitochondrial function of reprogrammed heart muscle cells. BIRMINGHAM, Ala ...

“Because centrosomes play such a fundamental role in heart muscle development, specifically cell replication, structure, and function, a better understanding of this tissue-specific programmed ...

The study was funded by an American Heart Association Postdoctoral Award (18POST33990469) the National Institutes of Health (R01 HL148714, R00 HL141626) and a Department of Defense Award (PR171540).

Heart muscle cells grown from stem cells show promise in monkeys with a heart problem that typically results from a heart defect sometimes present at birth in humans, according to new research ...