Adding zinc to the gem-chloride first generates an α-chlorine radical, where an iron-porphyrin catalyst subsequently converts ...

Research Highlights Published: 23 July 2015 Tetrahydrofuran synthesis Carbene reaction re-routed Stephen Davey Nature Chemistry 7, 615 (2015) Cite this article ...

The carbene reacts with an olefin to form a new olefin and a new metal carbene, thereby propagating the reaction, they hypothesized (Makromol. Chem. 1971, DOI: 10.1002/macp.1971.021410112).

Figure 2. Acceptor carbene insertion into C–H bonds is enabled by protein engineering. Blue = C–H insertion product; orange = cyclopropanation product. n.r. = no reaction. This burgeoning reactivity ...

In our previous study, we investigated the mechanism underlying the blue light-driven O–H functionalization of alcohols by MPDA. (8) We first demonstrated that MPDA does not exhibit photobasicity.

Reaction expands nitrogen-containing rings and options for medicinal chemists Reimagined 19th-century method could potentially take advantage of more than 1,600 commercially available reagents ...

The engineered bacteria used in the study metabolized sugars into carbene precursors and alkene substrates, and also expressed evolved P450 enzymes that use the carbene precursors and alkene ...