Translocations are indeed common in cancer cells ... Figure 2 shows an example of a spectral karyotype prepared from acute myeloid leukemia cells with multiple translocations, which are indicated ...

The risk of cancer goes up with age, in part because aging impedes the body's ability to detect and destroy cells with ...

Cancer cells are cells gone wrong — in other words, they no longer respond to many of the signals that control cellular growth and death. Cancer cells originate within tissues and, as they grow ...

5 Microscopy-based karyotyping methods such as DNA fluorescence ... Early genetic events in the life of cancer cells, such as changes in the maintenance of telomeric length, or the activation ...

Breast cancer is becoming increasingly treatable, but in some cases the disease can resurface even decades after a patient ...

Cancer research has mainly focused on identifying cancer-driver genes (CDGs) that may trigger tumorigenesis or promote aberrant cell growth. Modern large-scale sequencing of human cancers aims to ...

Use of a standardized cell-free (cf)DNA-sequencing and cancer-screening protocol detected ... abnormal and discordant with the fetal karyotype or chromosome microarray analysis, or nonreportable.

BMC Cancer 15: 260. doi: 10.1186/s12885-015-1297-7 (2015 ... “Dominant expansion of a cryptic subclone with an abnormal karyotype in B lymphoblastoid cell lines during culture.” Cytogen. Genome Res.