Most studies indicating involvement of calcium/calmodulin-dependent signaling pathways in heart disease have used transgenic mouse models in which constitutively active signaling molecules are ...

Calcium/calmodulin-dependent protein kinase II (CaMKII ... synaptic plasticity to include the modulation of cell death pathways. Aberrant CaMKII activation, or dysregulation of its structural ...

The first step in the primary chemical pathway for muscle contraction is for calcium in the muscle cell to combine with calmodulin. Then, the calcium/calmodulin complex "activates" a protein ...

Investigators at the University of Iowa found a link between inflammation in the heart muscle following a heart attack and a previously known enzyme called calcium/calmodulin-dependent protein ...

Interrupting the interaction between p68 and calcium-calmodulin, which is essential for cell migration, inhibited metastasis. The findings were recently published in Nature Communications.

When intracellular calcium is increased, it interacts with protein kinase C (PKC), calmodulin, and with other intracellular molecules, to activate downstream signaling pathways. To explore the ...

We discuss the pathway that mediates calcium signaling ... and phosphatases, and calcium-binding protein calmodulin (CaM) are all impacted by calcium activity. Because calcium signaling is ...

but by previously unknown pathways. CaM kinase II is a pivotal enzyme that registers changes in calcium levels and oxidative stress and translates these signals into cellular effects, including ...

In this movie, ultra-fast jGCaMP8 indicators were used to track the response in L2 neurons that are part of the “off” pathway ... to the calcium contains the protein calmodulin and a peptide ...

Calcium builds strong bones, good teeth--and healthy plants, according to a new study. Calcium builds strong bones, good teeth—and healthy plants, according to a new study from Washington State ...

Background: Wnt signaling affects fundamental development pathways by regulating cell proliferation ... Instead, spiperone increases intracellular calcium levels in a similar manner to ...