The FDA's approval of the first CRISPR-Cas9–based gene therapy marked a major milestone in biomedicine, validating genome ...

DNA replication is a fundamental biological process that enables the accurate duplication of an organism’s genetic material. This intricate mechanism ensures that each new cell receives a complete set ...

There's a fresh push to edit the genes of human embryos to prevent diseases and enhance characteristics that parents value.

CRISPR gene editing shows potential for treating genetic diseases. Explore how it may impact Down syndrome treatment and ...

GBA1 mutations impair ciliary Hedgehog signaling in Parkinson's disease, reducing neuroprotective factors and highlighting a ...

Researchers at Fred Hutch Cancer Center invented a new screening method called ReLiC that uses CRISPR-Cas9 to test all the ...

Earth's biodiversity is in crisis. An imminent "sixth mass extinction" threatens beloved and important wildlife. It also ...

The DNA origami provides a stable and precisely engineered platform for probe immobilization, overcoming issues of probe entanglement and irregular distribution that plague conventional SPR biosensors ...

The researchers used CRISPR to model loss-of-function mutations in murine hematopoietic cell lines, targeting six commonly mutated genes, namely, Trp53, Atm, Chd2, Samhd1, Mga, and Birc3.

Mar. 12, 2024 — Researchers found a way to screen cancer-linked gene mutations much more easily and quickly than existing approaches, using a variant of CRISPR genome-editing known as prime ...

While many genetic illnesses are due to point mutations, where a single DNA "letter" has been changed, the ability to work with longer sequences would broaden the technology's potential uses in both ...

The scientists used CRISPR gene editing tools to disable the mutation and restore treatment sensitivity to the cancer cells in a way that appears to minimize risks of dangerous side effects.