Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...

Researchers at Kumamoto University have successfully executed a practical trial of a new genome-editing technique that allows ...

Using gene editing with CRISPR-Cas9, the team has been able to study these proteins without altering ... Dec. 13, 2024 — Microorganisms produce a wide variety of natural products that can be ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases.

This study presents an enhanced nuclease prime editor (uPEn) that significantly improves gene knock-in and knockout efficiency in mammalian zygotes.

Gene editing, particularly CRISPR/Cas9-based systems, provides a more precise and efficient alternative. CRISPR/Cas9 allows for precise modifications to the genome, including knock-ins ...

But by combining a revolutionary new technology called CRISPR-Cas9 with a natural system known as a gene drive, theory is rapidly becoming reality. CRISPR places an entirely new kind of power into ...

The standard Cas9 protein cuts the DNA at the target. When the cut is repaired, mutations are introduced that usually disable a gene. This is by far the most common use of CRISPR. It’s called ...

Get Instant Summarized Text (Gist) New CRISPR-Cas systems have been identified, enhancing the gene editing toolkit. A notable system, SubCas9, from bacteria in dairy cows, is efficient, small, and ...

CRISPR libraries enable scientists to systematically investigate gene functions, identify novel drug targets, and develop personalized therapies.