The FDA's approval of the first CRISPR-Cas9–based gene therapy marked a major milestone in biomedicine, validating genome ...

DNA replication is a fundamental biological process that enables the accurate duplication of an organism’s genetic material. This intricate mechanism ensures that each new cell receives a complete set ...

Since its development a decade ago, CRISPR-cas9 has had many uses. In food, it can not only improve crop resilience to things ...

A team from UC San Diego, John Hopkins and UC Berkeley Universities found a way to edit a single gene in a mosquito that ...

Because gene SDR42E1 is involved in vitamin D metabolism, scientists could also target it in any of the many diseases.

CRISPR Therapeutics CRSP and Intellia Therapeutics NTLA are leading developers of therapies that utilize the Nobel Prize-winning CRISPR/Cas9 gene editing technology. While CRSP is the first and ...

When the gene editing tool CRISPR-Cas9 rocketed to fame more than a decade ago, it transformed biotechnology. Faster, cheaper, and safer than previous methods, the tool helped scientists gain insight ...

Strengthening oat as a crop will help protect the global food supply and safeguard communities from climate-driven food ...

CRISPR Therapeutics AG (CRSP) is a biotech firm pioneering gene-editing therapies leveraging its proprietary CRISPR/Cas9 platform. CRSP’s approved product is Casgevy, for the treatment of sickle ...

Over the past decade, the gene-editing tool CRISPR-Cas9 has revolutionized biology. With this molecular tool, researchers can target and cut specific locations in the DNA.

The CRISPR/Cas9 gene editing technology uses a human engineered guide RNA to lead an enzyme called Cas9 to a specific region of DNA. Cas9 acts like a pair of “molecular scissors” and cuts the DNA.

Even alternate versions of CRISPR, such as nickase Cas9 (nCas9) and dead Cas9 (dCas9), showed improved editing performance under autophagic conditions.