CRISPR/Cas (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated genes) is a small RNA-based adaptive prokaryotic immunity system that functions by acquisition of short ...

I will present recent mechanistic insights into CRISPR-Cas systems that reveal how bacteria adapt to rapidly evolving viruses. Learning Objectives: 1. An overview of the basic biology of CRISPR-Cas ...

Adaptive immunity in bacteria is controlled by a set of Cas proteins, which in a nutshell accomplish two different tasks: (i) When an invading phage inserts its genome into a bacterial cell but is not ...

The bacterial ‘adaptive’ immune system known as CRISPR-Cas destroys foreign DNA molecules, such as viral genomes, to which the cells have previously been exposed. Here, Hynes et al.show that ...

The CRISPR/Cas9 protein system, which is central part to bacterial adaptive immunity, ... Foreign DNA capture during CRISPR–Cas adaptive immunity. Nature, 2015; DOI: 10.1038/nature15760; ...

Amazingly, bacteria - although single celled organisms - often possess similar adaptive immunity called CRISPR/Cas systems. But the way that these CRISPR/Cas systems function is very much different to ...

The CRISPR-Cas [clustered regularly interspaced short palindromic repeats and the CRISPR-associated genes (Cas)] is an adaptive immune system of prokaryotes against the invasion of foreign genetic ...

Accompanying CRISPR sequences, there are 4-10 CRISPR-associated genes (cas), which are highly conserved and encode the Cas proteins. Cas proteins conduct adaptive immunity in prokaryotes (bacteria ...

The CRISPR-Cas system is a well-known adaptive immune system in bacteria, and a prominent mechanism for evading this immunity involves anti-CRISPR (Acr) proteins, which employ various methods to ...