However, in contrast to C3, the convertase ... to the rest of C5, this would probably not be sufficiently discriminatory against native C5 (discussed below). Measurements were made on a Biacore ...

Figure 4: CRIg inhibits C5 binding to the AP C5 convertase. In conclusion, CRIg, a novel Ig-superfamily complement receptor, binds primarily to the β-chain of C3b and C3c in a location that is ...