she noticed that cells do not tolerate the presence of unprotected chromosome ends, and that broken ends are quickly fused together by the DNA repair machinery. McClintock also saw that telomeres ...

"Intriguingly, Rad51 spreading only occurs on the chromosome where the break resides and does not "jump" to other chromosomes", says Kalocsay. As to the researchers knowledge, this is the first in ...

If it doesn’t, the resulting aneuploid cell is at an increased risk of a lagging chromosome and micronucleus formation. Shortened or broken telomeres can leave chromosomes vulnerable to fusion events ...

You have full access to this article via your institution. She also noticed that the progeny of plants with broken chromosomes had an unusually high frequency of variegation. Some showed a change ...

only a small amount of sequence information was transferred from the unbroken chromosome onto the broken chromosome. The remaining recombinants transferred a larger amount of sequence information, but ...