Notably, the research successfully reconstructed a hyperoside biosynthesis pathway in Escherichia coli BL21 (DE3), achieving a yield of 25 mg/l by feeding naringenin.

The biosynthetic pathway of specific steroidal compounds in nightshade plants (such as potatoes, tomatoes and eggplants) starts with cholesterol.

The pathway held a few surprises in store; contrary to expectations, the first step in the biosynthesis does not appear to be controlled by an enzyme, but instead occurs spontaneously.

Aroma volatiles are vital to fruit flavor and consumer preference, yet the genetic regulation of their biosynthesis remains ...

Now scientists have identified the biosynthetic pathway for one of those key precursors, baccatin III—which means that easier methods of paclitaxel manufacturing could be coming soon (Nature ...

We analyze the biosynthesis pathway of bioactive substances and construct substance production systems in microbial hosts. We create non-natural compounds by modifying biosynthetic pathways and enzyme ...

Flavonoids are important secondary metabolites in plants. The flavonoid biosynthesis pathway is regulated by various transcription factors, with MYB transcription factors considered to be the key ...

The purpose of the meeting was to confirm the FDA’s expectations for the proposed timing, format and content of the planned NDA submission. Based on feedback from the FDA, Disc plans to submit an NDA ...

Tsukuba, Japan—Researchers have been studying the transcription factor SREBP, a critical regulator of lipid biosynthesis. Precursor SREBP proteins, located in the endoplasmic reticulum (ER) of ...

This pathway reconstruction, along with optimization of feeding conditions and cofactor use, provides insights into the parallel biosynthesis routes of hyperoside in H. monogynum and demonstrates ...