Evidence-based recommendations on pemetrexed disodium (Alimta) for the maintenance treatment of non-small-cell lung cancer. Last reviewed: 10 August 2017 Text at the start of the recommendations ...

Osimertinib (Tagrisso, AstraZeneca) with pemetrexed and platinum-based chemotherapy is indicated for 'the first-line treatment of adult patients with advanced NSCLC whose tumours have EGFR exon 19 ...

Background: Pemetrexed (Alimta), a multi-targeted anti-folate, is synergisitic with gemcitabine in preclinical models. The optimal sequence and schedule of both drugs is currently unknown. This is the ...

The Food and Drug Administration (FDA) has approved Pemrydi RTU ® (pemetrexed injection), a ready-to-use (RTU) presentation of pemetrexed. The application was approved through the FDA’s 505 (b ...

AstraZeneca's Tagrisso (osimertinib) combined with pemetrexed and platinum-based chemotherapy has shown improvement in overall survival (OS) for those with first-line locally advanced or ...