A team of researchers at Karolinska Institutet has developed a novel tool for genetic research. The study, published in ...

This is necessary to deal with the enormous next generation sequencing datasets that emerge from each single-cell CRISPR screen ... natural killer cells, B cells and macrophages, so they ...

A library of guide RNAs—each targeting a unique gene for CRISPR-based interference and carrying a unique barcode sequence—is introduced into a population of cells at a concentration that results in ...

Widely used as a genome editing tool, the CRISPR-Cas9 system allows researchers to precisely induce frameshift mutations in specific genes or insert foreign nucleic acid sequences into a cell’s DNA.

CRISPR screening is a powerful method to investigate how the quantitative expression of certain genes affects complex cellular phenotypes and processes. With Chromium Single-Cell CRISPR Screening from ...

Human extracellular matrices can be edited in their composition using the CRISPR/Cas9 system, leading to materials exhibiting tailored regenerative capacities.

Northwestern Medicine investigators have developed a new avenue to reprogram compromised immune cells to act against ... performed a genome-wide CRISPR knockout screen to identify proteins that ...

Advances in the gene-editing technology known as CRISPR-Cas9 over ... Yale Stem Cell Center, and Yale Center for Biomedical Data Science. Matthew B. Dong and Xiaoyu Zhou, both of Yale's Department ...

Researchers at Tel Aviv University (TAU) successfully utilized CRISPR, a gene-editing technology, to remove a single gene from cancer cells in head and neck tumors. The study, conducted in animal ...

Advances in the gene-editing technology known as CRISPR-Cas9 over ... Yale Stem Cell Center, and Yale Center for Biomedical Data Science. Matthew B. Dong and Xiaoyu Zhou, both of Yale's Department ...