Uveitis is a serious condition where the uvea, the middle layer of the eye, is inflamed and can cause vision loss in two ways: structures of the eye break down, and light to the retina is blocked ...

Uveitis results from imbalance between inflammatory mechanisms and regulatory mechanisms. Several immune cells are involved in this process. The balance between T helper 17 (Th17) cells and ...

The eye is an immune-privileged tissue because of the need to keep blood vessels away from the central pathway of light and to restrict entry of inflammatory cells that could cause damage. This ...

An experimental autoimmune uveitis (EAU) mouse model was used to determine the impact of four doses (4, 40, 160 or 400 U/kg) of repository corticotrophin injection (RCI, an equivalent to ...

Oct 28 (Reuters) - TxCell SA : * Achieves positive results for Col-Treg in a model of autoimmune uveitis * Col-Treg is second product candidate from ASTrIA platform in model of autoimmune uveitis ...

Home Articles Transcription factor EGR2 alleviates autoimmune uveitis via activation of GDF15 to modulate the retinal microglial phenotype.

These findings contribute to a better understanding of the mechanisms behind anterior uveitis and its connection to common autoimmune diseases. Each year, approximately 600 Finns are diagnosed ...

Researchers from Sun Yat-Sen University and affiliated organizations presented data from a study that aimed to investigate mechanisms by which the CXC chemokine receptor 3 (CXCR3) antagonist, AMG-487, ...