This study reports important negative results by showing that genetic removal of the RNA-binding protein PTBP1 in astrocytes is not sufficient to induce their conversion into neurons, challenging ...

Working on cortical stem cells from rats, the researchers demonstrate that the bHLH transcription factor Ngn1, in addition to inducing neurogenesis, inhibits the differentiation of neural stem cells ...

This episode focuses on astrocytes, an essential cell type in the central nervous system (CNS), and how bit.bio's innovative technology is transforming research in this area. By watching this episode ...

Historically, researchers have struggled to work with physiologically relevant models of human astrocytes. Traditional methods of generating astrocytes from iPSCs, such as directed differentiation, ...

Figure 1. Immunocytochemistry demonstrating the expression of key astrocyte markers. Image Credit: Axol Bioscience Ltd Figure 2. Schematic of axoCellsastrocyte differentiation with intervention ...

Fatty diets and obesity affect the structure and function of astrocytes, the star-shaped brain cells located in the striatum, a brain region involved in the perception of pleasure generated by ...