Above: Imaging based on calcium levels in astrocytes demonstrates the effect of the team's intervention to activate Gq signaling with a chemical called CNO. Cells lit up bright orange upon CNO ...

"However, because astrocytic activity is largely driven by calcium dynamics, this tool is particularly well-suited for studying astrocytes." The researchers used the AstroLight tool to label and ...

Calcium signals in astrocytes are highly varied, ranging from small, local, uncoordinated elevations in [Ca 2+] to large, somatic [Ca 2+] increases that are coordinated between many cells, such as ...

Astrocytes are the largest and most prevalent type of glial cell in the central nervous system. Astrocytes contribute to formation of the blood–brain barrier, participate in the maintenance of ...

Get Instant Summarized Text (Gist) The study identifies distinct subtypes of white matter astrocytes, including a unique type with regenerative potential. Using advanced sequencing techniques ...

Here, we identified a circuit, locus coeruleus descending noradrenergic neurons projecting to the spinal dorsal horn (LC →SDH -NA neurons), that is activated by acute exposure to restraint stress and ...

Astrocytes play important roles in synaptic signaling, neurotransmitter synthesis and recycling, nutrient uptake, and control of local blood flow. Current projects include the generation and ...