The two main components of an antibody are the Fab fragment and the Fc fragment. The Fab is the section that binds the pathogen and modulates neutralization. The Fc fragment binds host cell Fc ...

One of the main factors determining therapeutic antibodies’ half-life is the interaction between the antibody’s Fc region and the neonatal Fc receptor (FcRn). FcRn is central to the body’s ability to ...

Understanding these glycosylation patterns is just as important as analyzing other tools like labeled peptides, which are ...

A collaborative team from the Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of ...

(I) Comparison of architecture and antibody binding footprint of HSV-1, HCMV, and EBV post-fusion gB in complex with its DII-specific antibody. The VH and VL of D48, SM5-1, and 3A3 were colored ...

Antibody-dependent cell-mediated cytotoxicity, a key effector function for the clinical efficacy of monoclonal antibodies, is mediated primarily through a set of closely related Fcγ receptors with ...