Antibodies are proteins with around 150 kDa molecular weight. They have a similar basic structure comprising of four polypeptide chains held together by disulfide bonds. These four polypeptide ...

The VH and VL of D48, SM5-1, and 3A3 were colored differently as (I). The domain color principle for cartoon diagrams for pre-fusion gB in complex with antibody was the same as (E).

In conventional antibodies, the light chain is bound to the constant region, CH1. However, in camelid antibodies, a single N-terminal variable domain heavy chain, referred to as VHH, binds to the ...

News Release 8-Jul-2022 Scientists analyze structure of antibodies that could be key to more effective cancer treatments Peer-Reviewed Publication University of Southampton ...

The structure of the teleost Immunoglobulin M core provides insights on polymeric antibody evolution, assembly, and function. Nature Communications, 2023; 14 (1) DOI: 10.1038/s41467-023-43240-z ...

SEATTLE--(BUSINESS WIRE)--Cyrus Biotechnology, Inc., today announced it has developed new antibody structure prediction software, Cyrus NextGen, that is significantly more accurate than other ...

Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation. Nature Communications, 2020; 11 (1) DOI: 10.1038/s41467-020-19231-9 ...

The α/β T cell receptor complex transmits signals from MHC/peptide antigens through a set of constitutively associated signaling molecules, including CD3-ε/γ and CD3-ε/δ. We report the crystal ...

Scientists at Fred Hutchinson Cancer Research Center in Seattle have shown that a potent antibody from a COVID-19 survivor interferes with a key feature on the surface of the coronavirus’s distinctive ...