We randomly assigned, in a 3:1 ratio, 44 patients with newly diagnosed ANCA-associated vasculitis and renal involvement to a standard glucocorticoid regimen plus either rituximab at a dose of 375 ...

Swedish investigators report high 1-year rates of renal and patient survival. Patients who have ANCA-associated vasculitis (AAV) with renal involvement have high short-term overall rates of renal ...

Figure 1: Renal biopsy findings in a patient with ANCA-associated vasculitis. Remission is achieved in the vast majority of patients with ANCA-associated vasculitis but a small number of patients ...

Patients with vs without ANCA-associated vasculitis are significantly more likely to die after kidney transplantation and to experience postoperative infection. Patients with ANCA-associated ...

Most children with ANCA-associated vasculitis had active kidney disease and impaired renal function at diagnosis. Those with normal or minimal kidney impairment had good chance of recovery.

“ANCA-associated vasculitis is associated with increased early mortality and a high risk of end-stage renal disease,” Peter A. Merkel, MD, MPH, chief of rheumatology and a professor of ...

When harmful bacteria or other microorganisms invade the body, neutrophils, a type of white blood cell, are one of the first immune cells to respond. They release powerful weapons to trap and kill ...

ANCA vasculitis may affect any organ, but it is most commonly seen in the lungs; the kidneys are also frequently involved. 2 ANCA vasculitis may present with constitutional symptoms and symptoms ...

It, however, presents with a classical triad of kidney, lung and upper respiratory ... In addition to MPA and WG, another form of ANCA-associated vasculitis, namely, CSS, has a wider range with ...

ANCA vasculitis can affect blood vessels in your kidneys and other organs. It’s not common, but your doctor can run a blood test to find out. You have other medical conditions. Lupus is only one ...