Amyloid deposits, as read on the Issalute portal of the Higher Institute of Health, "generally affect various organs such as the heart, kidneys, liver, or nervous system, leading to a partial or ...

A recent study led by a team of researchers at The Johns Hopkins University School of Medicine examining aging mice has ...

A group of disorders, called amyloid diseases, occurs due to proteins that form abnormal clumps and deposit in different organs, causing damage to the brain (AD, Parkinson's disease), heart (cardiac ...

People with Alzheimer’s disease have lower levels of lithium in their brains than those without cognitive impairment, and the ...

A recent study led by a team of researchers at The Johns Hopkins University School of Medicine examining aging mice has ...

“During long-term patisiran treatment, eGFR remained relatively stable in patients with ATTRv amyloidosis with polyneuropathy and impaired kidney function (baseline eGFR <60 mL/min/1.73 m 2 ...

KEY POINTS Transthyretin amyloidosis typically presents with entrapment neuropathy, polyneuropathy or heart failure; some patients may experience autonomic dysfunction or symptoms of central nervous ...

AstraZeneca’s anselamimab has failed to show any benefit in patients with light chain amyloidosis in two Phase III trials. A light chain depleter antibody, anselamimab was being investigated in the ...

Journal Reference: Vaishali Sanchorawala. Systemic Light Chain Amyloidosis. New England Journal of Medicine, 2024; 390 (24): 2295 DOI: 10.1056/NEJMra2304088 ...