From alveolar injury to extracellular matrix accumulation, the complex biology of pulmonary fibrosis is being unraveled ...

Generation of human alveolar epithelial type I cells from pluripotent stem cells. Journal: Cell Stem Cell Published: 2024-05-02 DOI: 10.1016/j.stem.2024.03.017 Affiliations: 5 Authors: 18 Go to ...

Researchers in China used machine learning to create diagnostic and prognostic models to aid in identifying idiopathic ...

Several studies have now demonstrated that trained immunity occurs in the airways to several pathogens and products, while its utility is yet to be determined.

Scripps’ lung medicine activates stem cells in the lower airways, known as type 2 alveolar epithelial (AEC2) cells, responsible for manufacturing crucial cells for exchanging stale oxygen for fresh.

Researchers in Japan have successfully generated lung cells similar to alveolar epithelial type 2 (AT2) cells from mouse embryonic fibroblasts without using stem cell technology. The AT2-like ...

“Our findings uniquely highlight the role of ATG5-mediated autophagy specifically within alveolar epithelial cells,” Professor Wu explained. “We demonstrated that when ATG5 is deficient, it ...

The UAB researchers showed that TREM2 — which stands for triggering receptors expressed on myeloid cells 2 — is predominantly expressed on monocyte-derived alveolar macrophages in bleomycin-induced ...

“The epithelial cells are making a signal kind of like a scream: ‘We got injured, we need repair, you need to come over here,’” says Sun-Min Yu, an engineer at the University of ...