The nodule produces a hormone, aldosterone, that controls how much salt is in the body. The new discovery is a gene variant in some of these nodules which leads to a vast, but intermittent, over ...

The fluctuating release of aldosterone throughout the day is also an issue for doctors, which at its peak causes salt overload and hypertension.

Researchers discovered a gene mutation that causes a common type of hypertension (high blood pressure) and a treatment for it. This study was published in the journal, 'Nature Genetics.' ...

Hypertension affects 1 in 3 adults worldwide and increases the risk of heart disease, heart attack and stroke. 30% of people with hypertension have dysregulated aldosterone, meaning that the body ...

Researchers delve into endocrine causes of hypertension (HTN), revealing key culprits like primary aldosteronism and Cushing's syndrome. The study also evaluates the efficacy of various treatments ...

Under-secretion of aldosterone causes Addison's disease (characterised by low blood pressure) whilst over-secretion causes Conn's syndrome, typified also by low levels of potassium.

What Causes CAH? CAH is a condition in which a gene that tells the body how to make an enzyme called 21-hydroxylase, which helps make cortisol and aldosterone, doesn't work properly.