Here’s how it works. Prader-Willi syndrome is caused by changes in gene expression in a specific portion of chromosome 15. Starting in childhood, it often leads to extreme, insatiable hunger.

Prader-Willi patients face a greater risk of cardiometabolic issues and other complications that stem from obesity. Redwood City, California-based Soleno estimates 300,000 to 400,000 people ...

Prader-Willi Syndrome, also called PWS, is a rare disorder that occurs in approximately one out of 22,000 births. The genetic disorder is characterized by chronic hunger, growth hormone deficiency ...