Although all segments of the preglomerular vasculature contribute to myogenic control of whole kidney autoregulation, the afferent arteriole provides the principle resistance adjustment determining ...

The kidney is probably critically involved in the development of essential hypertension, as in many genetic models of hypertension. We have investigated whether a narrowed renal afferent arteriole is ...

We present a new perfusion technique that allows arteries down to the level of capillaries to be fixed while relaxed and under a known intravascular pressure. Through a catheter inserted into the ...

Sgouralis, I. , & Layton, A. T. . (2012). Interactions between Tubuloglomerular Feedback and the Myogenic Mechanism of the Afferent Arteriole. Federation of American Societies for Experimental Biology ...

Calcium dynamics underlying the myogenic response of the renal afferent arteriole Citation: Edwards, A. , & Layton, A. T. . (2014). Calcium dynamics underlying the myogenic response of the renal ...

Afferent arterioles were either microperfused in vitro at 60 mm Hg to measure luminal diameter or incubated without microperfusion to assess renin release. When added to the bath, 10 (-10) or 10 (-9) ...

Although calcium antagonists exert preferential vasodilation of renal afferent arterioles, we have recently demonstrated that nilvadipine and efonidipine, possessing both L-type and T-type calcium ...

Adenosine, via activation of A 1 receptors on the afferent arteriole (AA), mediates the tubuloglomerular feedback (TGF) mechanism. Angiotensin II and nitric oxide (NO) can modulate the sensitivity of ...

Each kidney is made up of three sections: the renal cortex, the renal medulla and the renal pelvis. The blood arrives at the kidney via the renal artery, which splits into many afferent arterioles.

By microperfusing the afferent arteriole, in vitro, we have previously shown that vasoconstriction induced by intraluminal Ang II is much stronger in the superficial than in the juxtamedullary ...

Benidipine, an L- and T-type calcium channel blocker, dilates both efferent and afferent arterioles and reduces glomerular pressure. Thus, it may exert renoprotective effects. We conducted an open ...