“Our groundbreaking discovery, which is based on the right activation of the right T cells, builds on the foundations laid by T cell therapeutics such as checkpoint inhibitors, chimeric antigen ...

T helper (TH) cells are essential immune cells that help other immune cells function effectively. When activated in response ...

Current applications of CD40-directed cancer immunotherapy rely on the release of endogenous tumor antigen for T cell priming and activation. Here the authors develop a bispecific CD40 agonistic ...

Researchers developed SNIPRs, innovative receptors that sense soluble ligands, enabling precise therapeutic control in CAR ...

T-cells, a white blood cell in the immune system ... and function of the protein until it's triggered. The domain is activated by blue light, which switches the protein function on and off.

The researchers engineered cancer cells to re-express Parkin and found that Parkin contributes to the production of interferons, which activate and attract T cells to fight the tumor. The findings ...

T-cells, a white blood cell in the immune system ... and function of the protein until it's triggered. The domain is activated by blue light, which switches the protein function on and off.

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

BERKELEY, Calif.--(BUSINESS WIRE)--Nanotein Technologies, Inc. (“Nanotein”), a technology development company with next-generation immune cell activation reagents leveraging its proprietary ...

Title: Comprehensive biomarker analyses from a Phase 1 study reveals marked tumor microenvironment modulation in patients with advanced solid tumors treated with MP0317, a FAP-localized CD40 agonistic ...