Lymphocyte activation occurs when lymphocytes (B cells or T cells) are triggered through antigen-specific receptors on their cell surface. This causes the cells to proliferate and differentiate ...

Lymphocyte activation gene 3 (Lag3) is a protein expressed on various T-cell subsets, including Tregs, and has been ...

Researchers developed SNIPRs, innovative receptors that sense soluble ligands, enabling precise therapeutic control in CAR ...

Janux Therapeutics' innovative cancer treatment shows promise in reducing side effects and improving patient outcomes, but ...

T-cells, a white blood cell in the immune system ... and function of the protein until it's triggered. The domain is activated by blue light, which switches the protein function on and off.

To improve long-term persistence and reduce the risk of immune rejection, researchers are exploring ways to diminish the ...

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...