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In a 2021 publication, the Max Planck researchers produced the first detailed 3D image of the sarcomere, the basic contractile unit of skeletal and heart muscle cell that contains actin, myosin and, ...
Muscle contraction is the tightening, shortening, or lengthening of muscles when you do some activity. It can happen when you hold or pick up something, or when you stretch or exercise with weights.
The ACTN3 gene — also known as the “ speed gene ”— plays an important role in the actin and myosin contraction of muscle fibers. Professional sprinters possess the ACTN3 gene.
FRET and optical trapping reveal mechanisms of actin activation of the power stroke and phosphate release in myosin V. Journal of Biological Chemistry, 2020; 295 (51): 17383 DOI: 10.1074/jbc.RA120 ...
As expected, PP1c was translocated to the cell membrane upon blue light illumination being exposed upon the OptoMYPT expressing cells, and consequently, actin and myosin-mediated contractile force ...
The Burnham team, led by Dorit Hanein, Ph.D., was the first to reveal the 3D representation of myosin V "walking" along actin filament, a key protein involved in motility and muscle contraction.
The emergence of asymmetry from an initially symmetrical state is a universal transition in nature. Living organisms show asymmetries at the molecular, cellular, tissular, and organismal level.
At the molecular level, muscle contraction is defined by myosin molecules pulling actin filaments. New electron cryomicroscopy images with unprecedented resolution taken by researchers at Osaka ...
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