A recent study by University Medicine Halle shows how sepsis can lead to dysfunction of vascular smooth muscle cells. The researchers found that elevated lactate levels and acidosis, which can ...

The synergism of cytosolic acidosis and reduced NAD+/NADH ratio is responsible for lactic acidosis-induced vascular smooth muscle cell impairment in sepsis. J Biomed Sci. 2024 Jan 9;31 (1):3 ...

When the lactate was drawn (at the time of the code), and showed severe lactic acidosis, it was clear that our patient’s decompensation was because of severe sepsis and septic shock.

She died in the early hours of 24 January, 2022, after suffering a cardiac arrest. Her cause of death was sepsis and metabolic acidosis caused by kidney stones.

This study provides new insights into the potential mechanisms of sepsis progression and emphasizes the importance of continuous monitoring of ELL2 expression during early diagnosis and treatment.