A research team investigates how genome editing can be harnessed to accelerate cassava breeding and improve key traits.

“We are also now exploring ways to combine AAV vectors with gene-editing tools such as CRISPR/Cas9,” he says. Such hybrid technologies could overcome the capacity limitation (roughly 4.5 ...

3 Adeno-associated virus (AAV) vectors are used as the delivery carrier for CRISPR gene therapy, with the CRISPR system being packaged as plasmid DNA encoding its components such as Cas9 and guide ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into ...

A recent review published in the journal Engineering delves into the significant advancements and potential of CRISPR ...

Ensoma’s Cas12a-based editors, unlike CRISPR-associated protein 9 (Cas9)-based systems ... Versatile editors for AAV or RNA delivery To support RNA-based delivery, Ensoma engineered the RNA ...

The team replicated the approach with base and epigenetic editors that use other versions of Cas9, suggesting that it can be used with most CRISPR-based editors. Crucially, their results showed that a ...

When the CRISPR Cas9 protein is added to a cell along with a piece of guide RNA, the Cas9 protein hooks up with the guide RNA and then moves along the strands of DNA until it finds and binds to a ...

CRISPR Therapeutics AG is a gene editing company, which engages in the development of transformative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 platform.

Likewise, CRISPR/Cas9 has been pivotal in establishing in ... BEQVEZ is an adeno-associated virus (AAV)-based gene therapy ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...