The effects of OR3 on xenograft mouse models were evaluated by tumor volume measurement, hematological analysis, and histopathological observation. The characterization of OR3 was also performed ...

In the study, pH-dependent binding of MYTX-011 translated to potent efficacy in tumor xenografts regardless of mutation status, including models harboring MET exon 14 skipping, KRAS and EGFR ...

x mg/kg/week) TTV600, median (days) Mean (SD) tumor level (nmol/g) a,b Dose (# x mg/kg/week) TTV600, median (days) Mean (SD) tumor level (nmol/g) a,c ...

Scientists have created a new zebrafish xenograft platform to screen for novel treatments for an aggressive brain tumor called glioblastoma, according to a new study by the Gerhardt and De Smet ...

a first-in-class Wee1/Myt1 inhibitor through intermittent dosing for monotherapy and combination with chemotherapy in xenograft tumor models,” includes preclinical data demonstrating that SGR ...

XL092 as a single-agent and in combination with an anti-PD-1 antibody showed antitumor activity in xenograft tumor models (Hsu et al. 2020). This first-in-human study is evaluating safety, ...

Nuvectis Pharma Inc. has released promising data on NXP-800 in a preclinical xenograft model of ARID1a-mutated gastric carcinoma. NXP-800 results in tumor regression in xenograft model of ...

Researchers from Incyte Research Institute presented the discovery of a cyclin-dependent kinase 2 (CDK2) inhibitor, INCB-123667, being developed for the treatment of cyclin E dysregulated cancers.