The 4L80E contains a pan that is oval, while the 4L60E has one that is shaped like a rectangle. The number of bolts that both contain is also different. There is one gasket with 17 bolts on 4L80E ...

The Turbo-Hydramatic 700-R4, 4L60, electronic 4L60E, and the 4L65E, were all designed to replace the tried-and-true TH350. Read more in this Spotter's Guide.