Scientists have created a mega-database revealing how half a million different DNA mutations generate errors in proteins in humans. The researchers hope that the database will be used to develop ...

Publication information: “Modulation of lipid nanoparticle-formulated plasmid DNA drives innate immune activation promoting adaptive immunity,” from Cell Reports Medicine ...

In addition to exporting materials out of the nucleus, the protein, called Exportin-1 (also called Xpo1 or Crm1), seems to play a role in promoting gene transcription, the process that creates RNA ...

Genes have to be expressed in the right place, at the time, and at the right levels. Scientists wanted to know more about how ...

whereas muscle cells load themselves with the protein-based filaments necessary for muscle contractions. RNA molecules differ from DNA molecules in several important ways: They are single stranded ...

For the Liu Lab, necessity is truly the mother of invention. The researchers were examining how the 3D organization of the ...

This innovative method, based on chromatin immunoprecipitation (ChIP)—a technique utilized to isolate DNA fragments bound by ...

Abstract Genome-wide identification of binding profiles for DNA-binding proteins from the limited number of intracellular pathogens in infection ...

Scientists at Scripps Research have now captured the first detailed images of the DNA repair protein, Pol-theta, in action, revealing the molecular processes responsible for a range of cancers.

the Cas9 protein hooks up with the guide RNA and then moves along the strands of DNA until it finds and binds to a 20-DNA-letter long sequence that matches part of the guide RNA sequence.

In the February 12 Science Translational Medicine, they reported that taking down MSH3, a DNA repair protein, nipped CAG expansion in the bud. The DNA repair protein MSH3 promotes the growth of CAG ...