New 3D tissue model offers a breakthrough tool for understanding and treating scleroderma and other fibrotic diseases.

Research and drug discovery are undergoing a transformation, driven by the rise of 3D cell culture models that better replicate human biology. Unlike traditional 2D cultures and animal models, which ...

In this webinar, Kevin Grady and Manisha Nautiyal will outline how to make predictive 3D cell models for therapeutic ...

Organoids—self-organizing, self-reproducing structures that serve as 3D in vitro models—date back to 2009. Back then, researchers at the Hubrecht Institute led by Hans Clevers, PhD, introduced ...

For the 300,000 Americans living with the immune disease scleroderma, better treatments can't come soon enough. The rare and sometimes fatal illness ...

Quiescent horizontal basal stem cells act as a niche for olfactory neurogenesis in a mouse 3D organoid model. Cell Reports Methods. doi.org/10.1016/j.crmeth.2025.101055.

Infiltrating CD8+ T cells exacerbate Alzheimer’s disease pathology in a 3D human neuroimmune axis model. Nature Neuroscience, 2023; DOI: 10.1038/s41593-023-01415-3 ...