Disorders of cortisol biosynthesis can lead to congenital adrenal hyperplasia, the most common form of which is 21-hydroxylase deficiency (21-OHD). This Review details the clinical features and ...

NCAH is when your body doesn’t have enough 21-hydroxylase enzymes to make adrenal hormones. Learn about the causes, symptoms, and treatment for this condition.

Yes, I do think we need non-glucocorticoid forms of therapy to treat 21-hydroxylase deficiency congenital adrenal hyperplasia.The most common form of congenital adrenal hyperplasia (CAH) is a ...

A 21-hydroxylase deficiency is the most common form of CAH and affects around 1 in 10,000 to 1 in 15,000 people annually in the United States and Europe. In this article, we examine the types of ...

THIS report is concerned with the delineation and biochemical demonstration of a clinical syndrome first manifest in the adult woman and resulting from an 11β-hydroxylase deficiency in the ...

Patients with classic 21-hydroxylase deficiency require long-term glucocorticoid treatment to inhibit ... elimination of the excess adrenal androgen might reduce hirsutism and other such symptoms.

By Dr. Priyom Bose, Ph.D. Revolutionizing care for phenylalanine hydroxylase (PAH) deficiency, ACMG's updated guidelines highlight evidence-based strategies to enhance neurocognitive health and ...

In the pediatrics study, 103 participants aged 4 to 17 years old with classic CAH due to 21-hydroxylase deficiency and inadequate androgen control on supraphysiological glucocorticoid doses were ...

New observational Norwegian registry data reveal that Addison’s disease is almost exclusively autoimmune, and is associated with high autoimmune comorbidity. The observational study included a ...

Revolutionizing care for phenylalanine hydroxylase (PAH) deficiency, ACMG's updated guidelines highlight evidence-based strategies to enhance neurocognitive health and protect maternal and fetal ...