Researchers collected data from 345 children and adolescents aged 18 years and younger with a diagnosis of 21‐hydroxylase deficiency who were treated with oral hydrocortisone as a glucocorticoid ...

By Dr. Priyom Bose, Ph.D. Revolutionizing care for phenylalanine hydroxylase (PAH) deficiency, ACMG's updated guidelines highlight evidence-based strategies to enhance neurocognitive health and ...

Orlando, Florida — New data add to the evidence supporting use of crinecerfont for the treatment of congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency, in both adults and ...

Yes, I do think we need non-glucocorticoid forms of therapy to treat 21-hydroxylase deficiency congenital adrenal hyperplasia.The most common form of congenital adrenal hyperplasia (CAH) is a ...

Causes CAH occurs as a result of a deficiency in the enzyme 21-hydroxylase. This deficiency results in the adrenal glands producing too little sodium and too much androgen.

In the pediatrics study, 103 participants aged 4 to 17 years old with classic CAH due to 21-hydroxylase deficiency and inadequate androgen control on supraphysiological glucocorticoid doses were ...

The adrenal autoimmune process is made evident by the apperance of circulating autoantibodies against the steroidogenic enzyme 21-hydroxylase.