Notre Dame is 3-1. Notre Dame opened the season with a 23-13 victory over Texas A&M in College State, Texas, before falling in its home opener to Mid-American Conference school Northern Illinois, 16-14, in a stunner for the Irish. The Irish bounced back with a 66-7 victory at Purdue and then dispatched Miami (Ohio), 28-3, last weekend at home.

SportsLine's model just revealed its college football picks for Louisville Cardinals vs. Notre Dame Fighting Irish on Saturday

Notre Dame football picked up a huge win over Louisville on Saturday, beating the Cardinals 31-24 and moving to 4-1 on the season. It had large spells of offensive struggles for Notre Dame but was a game that saw Notre Dame lead for 49:59 of the 60-minute contest.

Keys to the drive: A lost fumble after a big run from Louisville quarterback Tyler Shough put the Irish at midfield. Jadarian Price had a 16-yard run, setting the table for the long Leonard touchdown pass. Drive: 1 play, 4 yards in three seconds after Louisville muffed a punt, causing a turnover on downs.

Regarding the actual game, the Louisville Cardinals boast multiple players that won’t be easy for Notre Dame to stop. We’ve made our predictions as to how Saturday afternoon will play out, along with some of the other top games across college football during Week 5.

Notre Dame running back Jeremiyah Love (4) falls into the end zone for a touchdown during a NCAA college football game between Notre Dame and Louisville at Notre Dame Stadium on Saturday, Sept. 28, 2024, in South Bend. / MICHAEL CLUBB/SOUTH BEND TRIBUNE / USA TODAY NETWORK via Imagn Images

Louisville vs Notre Dame football prediction, odds and how to watch college football Week 5 game. Here's what to know about Louisville football.

As his Louisville team prepares for Notre Dame Saturday, here's a look back at Jeff Brohm choosing the Cardinals over the Irish as a player in 1989

Now that the humble bragging is over let’s focus on Notre Dame at Louisville. When Notre Dame travels to Louisville, they are in a tough spot. Having played a tough ranked road

There are several things you need to see from Notre Dame during this stretch in order to feel good about how this 2024 team can be the rest of the season. It all starts with getti

The Notre Dame Fighting Irish can't catch a break. Fresh off their last game, they're on the road again, this time in Louisville, taking on another top-25 team.