Signal Transduction by Adhesion Receptors - Nature
WEBHow do cells forming organs or repairing tissues know when to stop growing? Adhesion receptors act as molecular fingertips that sense the environment and then coordinate behaviors.
Adhesion G protein-coupled receptors: structure, signaling, …
WEBOct 10, 2022 · This table displays the 33 adhesion G protein-coupled receptors (AGPCRs), organized by class, along with the documented G protein-dependent and alternate signaling pathways downstream of each receptor.
Adhesion protein structure, molecular affinities, and principles of ...
WEBApr 4, 2020 · We describe structures of select adhesion receptor complexes and their assembly into larger intercellular junction structures and discuss emerging principles that relate cell-cell organization to the binding specificities and …
The role and regulation of integrins in cell migration and invasion
WEB3 days ago · Integrin receptors connect cells to the extracellular matrix, mediating cell interactions, adhesion and signalling. This Review discusses integrin function in cell migration, including integrin ...
Revisiting T-cell adhesion molecules as potential targets for …
WEB2 days ago · The role of T-cell adhesion costimulatory receptors in regulating tumor immunity has been relatively underexplored.
Mechanisms of adhesion G protein–coupled receptor activation
WEBOct 9, 2020 · Adhesion G protein–coupled receptors (AGPCRs) are a thirty-three-member subfamily of Class B GPCRs that control a wide array of physiological processes and are implicated in disease. AGPCRs uniquely contain large, self-proteolyzing extracellular regions that range from hundreds to thousands of residues in length.
New Perspectives in Cell Adhesion: RGD and Integrins - Science
WEBTogether, the adhesion proteins and their receptors constitute a versatile recognition system providing cells with anchorage, traction for migration, and signals for polarity, position, differentiation, and possibly growth.
Conformational transitions and activation of the adhesion receptor …
WEBJan 11, 2024 · Adhesion G protein-coupled receptors (aGPCRs) are evolutionarily ancient receptors involved in a variety of physiological and pathophysiological processes. Modulators of aGPCR, particularly antagonists, hold therapeutic promise for diseases like cancer and immune and neurological disorders.
Cell Adhesion: The Molecular Basis of Tissue Architecture and ...
WEBFeb 9, 1996 · The functional units of cell adhesion are typically multiprotein complexes made up of three general classes of proteins; the cell adhesion molecules/adhesion receptors, the extracellular matrix (ECM) proteins, and the cytoplasmic plaque/peripheral membrane proteins.
Adhesion Receptor - an overview | ScienceDirect Topics
WEBIn addition to participating in cell adhesion, adhesion receptors transduce signals that regulate many aspects of cell behavior including movement, proliferation, differentiation, and survival.